Sex Specific Behavioral Profiles in Toddlers At Risk for Autism Spectrum Disorders (ASD)
نویسندگان
چکیده
The Positive Predictive Value (PPV) of the Modified Checklist for Autism in Toddlers (M-CHAT), a parent report autism screening tool, is higher for males than for females (Ludwig et al., IMFAR 2011). Given the long waitlists and high costs for ASD evaluations, there is a need to reduce the number of false positive females on the M-CHAT. The current study examined the sex specific clinical profiles of toddlers who received an ASD evaluation based on M-CHAT screen positive status in order to explore potential differences that may contribute to the differential PPV of the M-CHAT in boys and girls. The sample included 250 males and 106 females (mean age=25.3 months, SD=4.6) who were evaluated based on screen positive status on the M-CHAT. Although children with ASD demonstrated greater ASD symptoms, lower IQ and weaker language and motor skills, minimal sex differences were discovered. INDEX WORDS: Autism, Sex differences, M-CHAT, Screening SEX SPECIFIC BEHAVIORAL PROFILES IN TODDLERS AT RISK FOR AUTISM SPECTRUM DISORDERS (ASD)
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Parent-Endorsed Sex Differences in Toddlers with and Without ASD: Utilizing the M-CHAT
Sex differences in typical development can provide context for understanding ASD. Baron-Cohen (Trends Cogn Sci 6(6):248-254, 2002) suggested ASD could be considered an extreme expression of normal male, compared to female, phenotypic profiles. In this paper, sex-specific M-CHAT scores from N = 53,728 18-month-old toddlers, including n = 185 (32 females) with ASD, were examined. Results suggest ...
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